Highway 9 at Range Road 72 remains closed.
Crews are continuing to clear the collision scene which includes the recovery of the dangerous goods contained in one of the semi trucks.
The road blockage is still expected to last until approximately 12:00.
Three people involved in this collision were confirmed deceased on scene.
Two people were critically injured and transported via air ambulance to area hospitals.
Eight other people were injured and either treated on scene or transported to local hospitals.
Through the night, several RCMP detachments were involved in managing this incident, including Coronation, Redcliffe and Hanna.
The RCMP collision analyst attended. Support for people involved in the crash was received from the Victim Services Unit, including the use of the Oyen Legion.
The investigation into this collision remains a lengthy process given the nature of the crash scene.
It is anticipated that it will take several weeks for the collision analyst to complete the investigation.
If there is an update to be provided at that time, the RCMP will provide an update.
Shortly after 8:00 p.m. this evening, the fire was extinguished at the collision scene, and the RCMP collision analyst is on scene to conduct an examination and investigation.